@article{Israel2015-04nBack-38478,
  year={2015},
  doi={10.1016/j.pscychresns.2015.01.022},
  title={n-Back task performance and corresponding brain-activation patterns in women with restrictive and bulimic eating-disorder variants : Preliminary findings},
  number={1},
  volume={232},
  issn={0925-4927},
  journal={Psychiatry Research : Neuroimaging},
  pages={84--91},
  author={Israel, Mimi and Klein, Michael and Pruessner, Jens C. and Thaler, Lea and Spilka, Michael and Efanov, Simona and Ouellette, Anne-Sophie and Berlim, Marcelo and Ali, Nida and Steiger, Howard}
}

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    <dc:creator>Israel, Mimi</dc:creator>
    <dc:contributor>Israel, Mimi</dc:contributor>
    <dc:contributor>Berlim, Marcelo</dc:contributor>
    <dc:creator>Pruessner, Jens C.</dc:creator>
    <dc:creator>Spilka, Michael</dc:creator>
    <dc:creator>Efanov, Simona</dc:creator>
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    <dcterms:title>n-Back task performance and corresponding brain-activation patterns in women with restrictive and bulimic eating-disorder variants : Preliminary findings</dcterms:title>
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    <dc:contributor>Steiger, Howard</dc:contributor>
    <dc:contributor>Ouellette, Anne-Sophie</dc:contributor>
    <dc:contributor>Pruessner, Jens C.</dc:contributor>
    <dc:creator>Berlim, Marcelo</dc:creator>
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    <dc:contributor>Efanov, Simona</dc:contributor>
    <dc:contributor>Spilka, Michael</dc:contributor>
    <dcterms:issued>2015-04</dcterms:issued>
    <dcterms:abstract xml:lang="eng">Eating disorder (ED) variants characterized by "binge-eating/purging" symptoms differ from "restricting-only" variants along diverse clinical dimensions, but few studies have compared people with these different eating-disorder phenotypes on measures of neurocognitive function and brain activation. We tested the performances of 19 women with "restricting-only" eating syndromes and 27 with "binge-eating/purging" variants on a modified n-back task, and used functional magnetic resonance imaging (fMRI) to examine task-induced brain activations in frontal regions of interest. When compared with "binge-eating/purging" participants, "restricting-only" participants showed superior performance. Furthermore, in an intermediate-demand condition, "binge-eating/purging" participants showed significantly less event-related activation than did "restricting-only" participants in a right posterior prefrontal region spanning Brodmann areas 6-8-a region that has been linked to planning of motor responses, working memory for sequential information, and management of uncertainty. Our findings suggest that working memory is poorer in eating-disordered individuals with binge-eating/purging behaviors than in those who solely restrict food intake, and that observed performance differences coincide with interpretable group-based activation differences in a frontal region thought to subserve planning and decision making.</dcterms:abstract>
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    <dc:creator>Ali, Nida</dc:creator>
    <dc:creator>Ouellette, Anne-Sophie</dc:creator>
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    <dc:creator>Steiger, Howard</dc:creator>
    <dc:contributor>Klein, Michael</dc:contributor>
    <dc:contributor>Ali, Nida</dc:contributor>
    <dc:contributor>Thaler, Lea</dc:contributor>
    <dc:creator>Klein, Michael</dc:creator>
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