Publikation: Discovery of Teneurins
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Datum
2019
Autor:innen
Wides, Ron
Herausgeber:innen
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Open Access Gold
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Core Facility der Universität Konstanz
Titel in einer weiteren Sprache
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Published
Erschienen in
Frontiers in Neuroscience. 2019, 13, 230. ISSN 1662-4548. eISSN 1662-453X. Available under: doi: 10.3389/fnins.2019.00230
Zusammenfassung
Teneurins were first discovered and published in 1993 and 1994, in Drosophila melanogaster as Ten-a and Ten-m. They were initially described as cell surface proteins, and as pair-rule genes. Later, they proved to be type II transmembrane proteins, and not to be pair-rule genes. Ten-m might nonetheless have had an ancestral function in clock-based segmentation as a Ten-m oscillator. The turn of the millennium saw a watershed of vertebrate Teneurin discovery, which was soon complemented by Teneurin protein annotations from whole genome sequence publications. Teneurins encode proteins with essentially invariant domain order and size. The first years of Teneurin studies in many experimental systems led to key insights, and a unified picture, of Teneurin proteins.
Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
570 Biowissenschaften, Biologie
Schlagwörter
teneurin, ten-m, ten-a, TENM, ODZ, latrophilin, type II transmembrane protein, Drosophila
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ISO 690
BAUMGARTNER, Stefan, Ron WIDES, 2019. Discovery of Teneurins. In: Frontiers in Neuroscience. 2019, 13, 230. ISSN 1662-4548. eISSN 1662-453X. Available under: doi: 10.3389/fnins.2019.00230BibTex
@article{Baumgartner2019Disco-47145,
year={2019},
doi={10.3389/fnins.2019.00230},
title={Discovery of Teneurins},
volume={13},
issn={1662-4548},
journal={Frontiers in Neuroscience},
author={Baumgartner, Stefan and Wides, Ron},
note={Article Number: 230}
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