Discovery of Teneurins

Baumgartner, Stefan; Wides, Ron

Discovery of Teneurins

Dateien

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Datum

2019

Autor:innen

Baumgartner, Stefan

Wides, Ron

Open Access-Veröffentlichung

Open Access Gold

Sammlungen

Biologie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Frontiers in Neuroscience. 2019, 13, 230. ISSN 1662-4548. eISSN 1662-453X. Available under: doi: 10.3389/fnins.2019.00230

Zusammenfassung

Teneurins were first discovered and published in 1993 and 1994, in Drosophila melanogaster as Ten-a and Ten-m. They were initially described as cell surface proteins, and as pair-rule genes. Later, they proved to be type II transmembrane proteins, and not to be pair-rule genes. Ten-m might nonetheless have had an ancestral function in clock-based segmentation as a Ten-m oscillator. The turn of the millennium saw a watershed of vertebrate Teneurin discovery, which was soon complemented by Teneurin protein annotations from whole genome sequence publications. Teneurins encode proteins with essentially invariant domain order and size. The first years of Teneurin studies in many experimental systems led to key insights, and a unified picture, of Teneurin proteins.

Fachgebiet (DDC)

570 Biowissenschaften, Biologie

Schlagwörter

teneurin, ten-m, ten-a, TENM, ODZ, latrophilin, type II transmembrane protein, Drosophila

Zitieren

ISO 690

BAUMGARTNER, Stefan, Ron WIDES, 2019. Discovery of Teneurins. In: Frontiers in Neuroscience. 2019, 13, 230. ISSN 1662-4548. eISSN 1662-453X. Available under: doi: 10.3389/fnins.2019.00230

BibTex

@article{Baumgartner2019Disco-47145,
  year={2019},
  doi={10.3389/fnins.2019.00230},
  title={Discovery of Teneurins},
  volume={13},
  issn={1662-4548},
  journal={Frontiers in Neuroscience},
  author={Baumgartner, Stefan and Wides, Ron},
  note={Article Number: 230}
}

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Begutachtet

Ja