Application of laser-capture microdissection to study renal carcinogenesis
Application of laser-capture microdissection to study renal carcinogenesis
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2011
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Laser capture microdissection : methods and protocols / Graeme I. Murray (ed.). - 2. - Totowa , NJ : Humana Press, 2011. - (Methods in molecular biology ; 755). - pp. 279-290. - ISBN 978-1-61779-162-8
Abstract
Kidney cancer is characterized by significant morphological and molecular heterogeneity. Evaluation of mechanisms involved in the development and progression of kidney cancer require comprehensive analyses of genomes, transcriptomes, proteomes, and methylation profiles in normal and tumor tissue. To date, indiscriminate homogenates of tumor tissue or biopsy samples have been used as a source for DNA, RNA, or protein isolation. A major technical improvement has been the development of laser-assisted microdissection that allows the isolation of morphologically similar cells. The applications of this technology to kidney cancer research are outlined.
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STEMMER, Kerstin, Daniel R. DIETRICH, 2011. Application of laser-capture microdissection to study renal carcinogenesis. In: GRAEME I. MURRAY, , ed.. Laser capture microdissection : methods and protocols. 2. Totowa , NJ:Humana Press, pp. 279-290. ISBN 978-1-61779-162-8. Available under: doi: 10.1007/978-1-61779-163-5_23BibTex
@incollection{Stemmer2011Appli-16513, year={2011}, doi={10.1007/978-1-61779-163-5_23}, title={Application of laser-capture microdissection to study renal carcinogenesis}, edition={2}, number={755}, isbn={978-1-61779-162-8}, publisher={Humana Press}, address={Totowa , NJ}, series={Methods in molecular biology}, booktitle={Laser capture microdissection : methods and protocols}, pages={279--290}, editor={Graeme I. Murray}, author={Stemmer, Kerstin and Dietrich, Daniel R.} }
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