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Application of laser-capture microdissection to study renal carcinogenesis

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2011

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http://nbn-resolving.de/urn:nbn:de:bsz:352-165135
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https://doi.org/10.1007/978-1-61779-163-5_23
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GRAEME I. MURRAY, , ed.. Laser capture microdissection : methods and protocols. 2. Totowa , NJ: Humana Press, 2011, pp. 279-290. Methods in molecular biology. 755. ISBN 978-1-61779-162-8. Available under: doi: 10.1007/978-1-61779-163-5_23

Zusammenfassung

Kidney cancer is characterized by significant morphological and molecular heterogeneity. Evaluation of mechanisms involved in the development and progression of kidney cancer require comprehensive analyses of genomes, transcriptomes, proteomes, and methylation profiles in normal and tumor tissue. To date, indiscriminate homogenates of tumor tissue or biopsy samples have been used as a source for DNA, RNA, or protein isolation. A major technical improvement has been the development of laser-assisted microdissection that allows the isolation of morphologically similar cells. The applications of this technology to kidney cancer research are outlined.

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570 Biowissenschaften, Biologie

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ISO 690STEMMER, Kerstin, Daniel R. DIETRICH, 2011. Application of laser-capture microdissection to study renal carcinogenesis. In: GRAEME I. MURRAY, , ed.. Laser capture microdissection : methods and protocols. 2. Totowa , NJ: Humana Press, 2011, pp. 279-290. Methods in molecular biology. 755. ISBN 978-1-61779-162-8. Available under: doi: 10.1007/978-1-61779-163-5_23
BibTex
@incollection{Stemmer2011Appli-16513,
  year={2011},
  doi={10.1007/978-1-61779-163-5_23},
  title={Application of laser-capture microdissection to study renal carcinogenesis},
  edition={2},
  number={755},
  isbn={978-1-61779-162-8},
  publisher={Humana Press},
  address={Totowa , NJ},
  series={Methods in molecular biology},
  booktitle={Laser capture microdissection : methods and protocols},
  pages={279--290},
  editor={Graeme I. Murray},
  author={Stemmer, Kerstin and Dietrich, Daniel R.}
}
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