The role of octopamine and tyramine in Drosophila larval locomotion

Lade...
Vorschaubild
Dateien
Selcho_217701.pdf
Selcho_217701.pdfGröße: 11.45 MBDownloads: 2049
Datum
2012
Autor:innen
Selcho, Mareike
Pauls, Dennis
Jundi, Basil el
Stocker, Reinhard F.
Herausgeber:innen
Kontakt
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
DOI (zitierfähiger Link)
ArXiv-ID
Internationale Patentnummer
EU-Projektnummer
DFG-Projektnummer
Projekt
Open Access-Veröffentlichung
Gesperrt bis
Titel in einer weiteren Sprache
Forschungsvorhaben
Organisationseinheiten
Zeitschriftenheft
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
unikn.publication.listelement.citation.prefix.version.undefined
The Journal of Comparative Neurology. 2012, 520(16), pp. 3764-3785. ISSN 0021-9967. eISSN 1096-9861. Available under: doi: 10.1002/cne.23152
Zusammenfassung

The characteristic crawling behavior of Drosophila larvae consists of a series of rhythmic waves of peristalsis and episodes of head swinging and turning. The two biogenic amines octopamine and tyramine have recently been shown to modulate various parameters of locomotion, such as muscle contraction, the time spent in pausing or forward locomotion, and the initiation and maintenance of rhythmic motor patterns. By using mutants having altered octopamine and tyramine levels and by genetic interference with both systems we confirm that signaling of these two amines is necessary for larval locomotion. We show that a small set of about 40 octopaminergic/tyraminergic neurons within the ventral nerve cord is sufficient to trigger proper larval locomotion. Using single-cell clones, we describe the morphology of these neurons individually. Given various potential roles of octopamine and tyramine in the larval brain, such as locomotion, learning and memory, stress-induced behaviors or the regulation of the energy state, functions that are often not easy to discriminate, we dissect here for the first time a subset of this complex circuit that modulates specifically larval locomotion. Thus, these data will help to understand—for a given neuronal modulator—how specific behavioral functions are executed within distinct subcircuits of a complex neuronal network

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
570 Biowissenschaften, Biologie
Schlagwörter
Konferenz
Rezension
undefined / . - undefined, undefined
Zitieren
ISO 690SELCHO, Mareike, Dennis PAULS, Basil el JUNDI, Reinhard F. STOCKER, Andreas THUM, 2012. The role of octopamine and tyramine in Drosophila larval locomotion. In: The Journal of Comparative Neurology. 2012, 520(16), pp. 3764-3785. ISSN 0021-9967. eISSN 1096-9861. Available under: doi: 10.1002/cne.23152
BibTex
@article{Selcho2012-11-01octop-21770,
  year={2012},
  doi={10.1002/cne.23152},
  title={The role of octopamine and tyramine in Drosophila larval locomotion},
  number={16},
  volume={520},
  issn={0021-9967},
  journal={The Journal of Comparative Neurology},
  pages={3764--3785},
  author={Selcho, Mareike and Pauls, Dennis and Jundi, Basil el and Stocker, Reinhard F. and Thum, Andreas}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/21770">
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dc:rights>terms-of-use</dc:rights>
    <dcterms:bibliographicCitation>Journal of Comparative Neurology ; 520 (2012), 16. - S. 3764-3785</dcterms:bibliographicCitation>
    <dc:language>eng</dc:language>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dcterms:issued>2012-11-01</dcterms:issued>
    <dc:creator>Jundi, Basil el</dc:creator>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/21770"/>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2013-02-13T15:51:35Z</dcterms:available>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/52"/>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/52"/>
    <dcterms:abstract xml:lang="eng">The characteristic crawling behavior of Drosophila larvae consists of a series of rhythmic waves of peristalsis and episodes of head swinging and turning. The two biogenic amines octopamine and tyramine have recently been shown to modulate various parameters of locomotion, such as muscle contraction, the time spent in pausing or forward locomotion, and the initiation and maintenance of rhythmic motor patterns. By using mutants having altered octopamine and tyramine levels and by genetic interference with both systems we confirm that signaling of these two amines is necessary for larval locomotion. We show that a small set of about 40 octopaminergic/tyraminergic neurons within the ventral nerve cord is sufficient to trigger proper larval locomotion. Using single-cell clones, we describe the morphology of these neurons individually. Given various potential roles of octopamine and tyramine in the larval brain, such as locomotion, learning and memory, stress-induced behaviors or the regulation of the energy state, functions that are often not easy to discriminate, we dissect here for the first time a subset of this complex circuit that modulates specifically larval locomotion. Thus, these data will help to understand—for a given neuronal modulator—how specific behavioral functions are executed within distinct subcircuits of a complex neuronal network</dcterms:abstract>
    <dc:contributor>Selcho, Mareike</dc:contributor>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <dc:contributor>Pauls, Dennis</dc:contributor>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/21770/1/Selcho_217701.pdf"/>
    <dc:contributor>Jundi, Basil el</dc:contributor>
    <dc:contributor>Stocker, Reinhard F.</dc:contributor>
    <dc:contributor>Thum, Andreas</dc:contributor>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/21770/1/Selcho_217701.pdf"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2013-02-13T15:51:35Z</dc:date>
    <dc:creator>Stocker, Reinhard F.</dc:creator>
    <dc:creator>Selcho, Mareike</dc:creator>
    <dc:creator>Pauls, Dennis</dc:creator>
    <dcterms:title>The role of octopamine and tyramine in Drosophila larval locomotion</dcterms:title>
    <dc:creator>Thum, Andreas</dc:creator>
  </rdf:Description>
</rdf:RDF>
Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Kontakt
URL der Originalveröffentl.
Prüfdatum der URL
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet