New insights into coenzyme A interaction with mercury ions provided by mass spectrometric and circular dichroism spectroscopic approaches

Andries, Claudia; Manea, Marilena; Drochioiu, Gabi; Gradinaru, Robert

New insights into coenzyme A interaction with mercury ions provided by mass spectrometric and circular dichroism spectroscopic approaches

Dateien

Zu diesem Dokument gibt es keine Dateien.

Datum

2015

Autor:innen

Andries, Claudia

Manea, Marilena

Drochioiu, Gabi

Gradinaru, Robert

DOI (zitierfähiger Link)

https://doi.org/10.1255/ejms.1361

Sammlungen

Chemie
Zukunftskolleg

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

European Journal of Mass Spectrometry : EJMS. 2015, 21(2), pp. 97-102. ISSN 1469-0667. eISSN 1751-6838. Available under: doi: 10.1255/ejms.1361

Zusammenfassung

The interaction of coenzyme A (CoA) with mercury ions was investigated using electrospray ionization mass spectrometry and circular dichroism spectroscopy. Our results indicated a 1:1 stoichiometric CoA-Hg complex at physiological pH. Furthermore, the CoA conformation considerably changed in the presence of mercury ions. In addition, a by-product of the reaction, thiocoenzyme A, was identified using mass spectrometry.

Fachgebiet (DDC)

540 Chemie

Zitieren

ISO 690

ANDRIES, Claudia, Marilena MANEA, Gabi DROCHIOIU, Robert GRADINARU, 2015. New insights into coenzyme A interaction with mercury ions provided by mass spectrometric and circular dichroism spectroscopic approaches. In: European Journal of Mass Spectrometry : EJMS. 2015, 21(2), pp. 97-102. ISSN 1469-0667. eISSN 1751-6838. Available under: doi: 10.1255/ejms.1361

BibTex

@article{Andries2015insig-31612,
  year={2015},
  doi={10.1255/ejms.1361},
  title={New insights into coenzyme A interaction with mercury ions provided by mass spectrometric and circular dichroism spectroscopic approaches},
  number={2},
  volume={21},
  issn={1469-0667},
  journal={European Journal of Mass Spectrometry : EJMS},
  pages={97--102},
  author={Andries, Claudia and Manea, Marilena and Drochioiu, Gabi and Gradinaru, Robert}
}

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