Cobalt-mediated regioselective synthesis of substituted tetrahydroquinolines
Cobalt-mediated regioselective synthesis of substituted tetrahydroquinolines
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2005
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Synlett ; 2005, 11. - pp. 1758-1760. - ISSN 0936-5214. - eISSN 1437-2096
Abstract
A regioselective synthesis of polycyclic substituted pyridines is reported. Key step is the cobalt-catalyzed intramolecular cyclization of diynenitriles, tethered by a silicon oxygen bond. Subsequent opening of the Si-O ring led then to the related tetrahydroquinolines.
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540 Chemistry
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cobalt,catalysis,cycloaddition,pyridines,quinolines,ergot alkaloids
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GROTH, Ulrich, Thomas HUHN, Christian KESENHEIMER, Aris KALOGERAKIS, 2005. Cobalt-mediated regioselective synthesis of substituted tetrahydroquinolines. In: Synlett(11), pp. 1758-1760. ISSN 0936-5214. eISSN 1437-2096. Available under: doi: 10.1055/s-2005-871568BibTex
@article{Groth2005Cobal-9820, year={2005}, doi={10.1055/s-2005-871568}, title={Cobalt-mediated regioselective synthesis of substituted tetrahydroquinolines}, number={11}, issn={0936-5214}, journal={Synlett}, pages={1758--1760}, author={Groth, Ulrich and Huhn, Thomas and Kesenheimer, Christian and Kalogerakis, Aris} }
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