Synthesis of Enantiomerically Pure Diethyl 2-Pyrrolidinyl- and 5-0xo-2-pyrrolidinylphosphonates

dc.contributor.authorGroth, Ulrich
dc.contributor.authorRichter, Lutzdeu
dc.contributor.authorSchöllkopf, Ulrichdeu
dc.date.accessioned2011-03-24T18:15:00Zdeu
dc.date.available2011-03-24T18:15:00Zdeu
dc.date.issued1992deu
dc.description.abstractEnantiomerically pure 3- and 4-substituted phosphonic acid derivatives 5 of pyroglutamic acid were prepared by a Michael addition of the lithiated (+)-camphor derivative 2 to α,β-unsaturated esters and subsequent hydrolysis. The reduction of the lactams 5 with LiBH4/BF3·OEtz afforded substituted phosphonic acid analogues 7 of proline.deu
dc.description.versionpublished
dc.format.mimetypeapplication/pdfdeu
dc.identifier.citationFirst publ. in: Liebigs Annalen der Chemie 1992, 9, pp. 903-909deu
dc.identifier.doi10.1002/jlac.1992199201150
dc.identifier.ppn276790138deu
dc.identifier.urihttp://kops.uni-konstanz.de/handle/123456789/9874
dc.language.isoengdeu
dc.legacy.dateIssued2008deu
dc.rightsAttribution-NonCommercial-NoDerivs 2.0 Generic
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.0/
dc.subjectPhosphoglutamic acidsdeu
dc.subjectPhosphoprolinesdeu
dc.subjectMichael additionsdeu
dc.subjectLactamsdeu
dc.subject.ddc540deu
dc.titleSynthesis of Enantiomerically Pure Diethyl 2-Pyrrolidinyl- and 5-0xo-2-pyrrolidinylphosphonateseng
dc.typeJOURNAL_ARTICLEdeu
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@article{Groth1992Synth-9874,
  year={1992},
  doi={10.1002/jlac.1992199201150},
  title={Synthesis of Enantiomerically Pure Diethyl 2-Pyrrolidinyl- and 5-0xo-2-pyrrolidinylphosphonates},
  number={9},
  volume={1992},
  issn={0170-2041},
  journal={Liebigs Annalen der Chemie},
  pages={903--909},
  author={Groth, Ulrich and Richter, Lutz and Schöllkopf, Ulrich}
}
kops.citation.iso690GROTH, Ulrich, Lutz RICHTER, Ulrich SCHÖLLKOPF, 1992. Synthesis of Enantiomerically Pure Diethyl 2-Pyrrolidinyl- and 5-0xo-2-pyrrolidinylphosphonates. In: Liebigs Annalen der Chemie. 1992, 1992(9), pp. 903-909. ISSN 0170-2041. eISSN 1099-0690. Available under: doi: 10.1002/jlac.1992199201150deu
kops.citation.iso690GROTH, Ulrich, Lutz RICHTER, Ulrich SCHÖLLKOPF, 1992. Synthesis of Enantiomerically Pure Diethyl 2-Pyrrolidinyl- and 5-0xo-2-pyrrolidinylphosphonates. In: Liebigs Annalen der Chemie. 1992, 1992(9), pp. 903-909. ISSN 0170-2041. eISSN 1099-0690. Available under: doi: 10.1002/jlac.1992199201150eng
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