Visual discrimination in pigeons impaired by glutamatergic blockade of nucleus accumbens

Lade...
Vorschaubild
Dateien
Delius Visual discrimination.pdf
Delius Visual discrimination.pdfGröße: 99.34 KBDownloads: 326
Datum
1998
Autor:innen
Gargiulo, Pascual A.
Siemann, Martina
Herausgeber:innen
Kontakt
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
ArXiv-ID
Internationale Patentnummer
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Open Access Green
Sammlungen
Core Facility der Universität Konstanz
Gesperrt bis
Titel in einer weiteren Sprache
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published
Erschienen in
Physiology & Behavior. 1998, 63(4), pp. 705-709. ISSN 0031-9384. Available under: doi: 10.1016/S0031-9384(97)00516-7
Zusammenfassung

The nucleus accumbens septi (Acc) is thought to be involved in the control of cognitive processes and to be implicated in the pathophysiology of schizophrenia. Because perceptual-cognitive distortions are a core symptom in schizophrenia, any evidence that the Acc intervenes in a sensory recognition task in an animal species would be of interest. Pigeons were instrumentally trained to discriminate visual shapes. The acute effects of drug microinjections into the Acc on the discrimination of the training shapes, on the correction responding after errors, and on the generalisation to different shapes were examined. The effects of conduction blockade with lidocaine, glutamatergic blockade with 7-aminophosphonoheptanoic acid, and dopaminergic stimulation with apomorphine on behavioural performance were tested. No effects were observed with lidocaine and apomorphine. A significant and reversible performance disruption to near chance levels was obtained after aminophosphonoheptanoic acid injections into the Acc. It appears that a glutamatergic blockade of the Acc interferes with the visual discrimination processes of pigeons.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
150 Psychologie
Schlagwörter
Nucleus accumbens, pigeons, visual discrimination, glutamatergic blockade, dopaminergic activation
Konferenz
Rezension
undefined / . - undefined, undefined
Forschungsvorhaben
Organisationseinheiten
Zeitschriftenheft
Datensätze
Zitieren
ISO 690GARGIULO, Pascual A., Martina SIEMANN, Juan DELIUS, 1998. Visual discrimination in pigeons impaired by glutamatergic blockade of nucleus accumbens. In: Physiology & Behavior. 1998, 63(4), pp. 705-709. ISSN 0031-9384. Available under: doi: 10.1016/S0031-9384(97)00516-7
BibTex
@article{Gargiulo1998Visua-20492,
  year={1998},
  doi={10.1016/S0031-9384(97)00516-7},
  title={Visual discrimination in pigeons impaired by glutamatergic blockade of nucleus accumbens},
  number={4},
  volume={63},
  issn={0031-9384},
  journal={Physiology & Behavior},
  pages={705--709},
  author={Gargiulo, Pascual A. and Siemann, Martina and Delius, Juan}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/20492">
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/20492/1/Delius%20Visual%20discrimination.pdf"/>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2012-10-10T09:45:05Z</dcterms:available>
    <dcterms:title>Visual discrimination in pigeons impaired by glutamatergic blockade of nucleus accumbens</dcterms:title>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/20492"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2012-10-10T09:45:05Z</dc:date>
    <dc:contributor>Gargiulo, Pascual A.</dc:contributor>
    <dc:creator>Gargiulo, Pascual A.</dc:creator>
    <dc:creator>Siemann, Martina</dc:creator>
    <dc:contributor>Delius, Juan</dc:contributor>
    <dc:creator>Delius, Juan</dc:creator>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/20492/1/Delius%20Visual%20discrimination.pdf"/>
    <dcterms:issued>1998</dcterms:issued>
    <dcterms:abstract xml:lang="eng">The nucleus accumbens septi (Acc) is thought to be involved in the control of cognitive processes and to be implicated in the pathophysiology of schizophrenia. Because perceptual-cognitive distortions are a core symptom in schizophrenia, any evidence that the Acc intervenes in a sensory recognition task in an animal species would be of interest. Pigeons were instrumentally trained to discriminate visual shapes. The acute effects of drug microinjections into the Acc on the discrimination of the training shapes, on the correction responding after errors, and on the generalisation to different shapes were examined. The effects of conduction blockade with lidocaine, glutamatergic blockade with 7-aminophosphonoheptanoic acid, and dopaminergic stimulation with apomorphine on behavioural performance were tested. No effects were observed with lidocaine and apomorphine. A significant and reversible performance disruption to near chance levels was obtained after aminophosphonoheptanoic acid injections into the Acc. It appears that a glutamatergic blockade of the Acc interferes with the visual discrimination processes of pigeons.</dcterms:abstract>
    <dc:contributor>Siemann, Martina</dc:contributor>
    <dcterms:bibliographicCitation>Physiology &amp; Behavior ; 63 (1998), 4. - S. 705-709</dcterms:bibliographicCitation>
    <dc:language>eng</dc:language>
    <dc:rights>terms-of-use</dc:rights>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/>
  </rdf:Description>
</rdf:RDF>
Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Kontakt
URL der Originalveröffentl.
Prüfdatum der URL
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Begutachtet
Diese Publikation teilen