Publikation:

NMR.-study of nitrogen inversion and conformation of 1,5-dihydro-isoalloxazines ('Reduced Flavin')

Lade...
Vorschaubild

Dateien

NMR.pdf
NMR.pdfGröße: 959.93 KBDownloads: 711

Datum

1973

Autor:innen

Tauscher, Ludwig
Hemmerich, Peter

Herausgeber:innen

Kontakt

ISSN der Zeitschrift

Electronic ISSN

ISBN

Bibliografische Daten

Verlag

Schriftenreihe

Auflagebezeichnung

ArXiv-ID

Internationale Patentnummer

Angaben zur Forschungsförderung

Projekt

Open Access-Veröffentlichung
Open Access Green
Core Facility der Universität Konstanz

Gesperrt bis

Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

Helvetica Chimica Acta. 1973, 56(2), pp. 630-644. ISSN 0018-019X. eISSN 1522-2675. Available under: doi: 10.1002/hlca.19730560209

Zusammenfassung

Thc pyramidal inversion of the N(5)-centre of several reduced flavins was measured by NMR. The inversion barrier was found to be ~10 kcal/mol in acetone solutions and to be independent of the size of the N(5) substituent. An increase of the inversion barrier of ~5 kcal/mol was observed in the case where the N(5) substituent could only be in axial position, and an increase of ~3.5 kcal/mol was observed for an acyl-like N(5) substituent. In aqueous solution the inversion barrier increases by ~3 kcal/mol. The stereochemistry of reduced flavin and its potential relevance in flavin-dependent biological dehydrogenations is discussed.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
570 Biowissenschaften, Biologie

Schlagwörter

Konferenz

Rezension
undefined / . - undefined, undefined

Forschungsvorhaben

Organisationseinheiten

Zeitschriftenheft

Zugehörige Datensätze in KOPS

Zitieren

ISO 690TAUSCHER, Ludwig, Sandro GHISLA, Peter HEMMERICH, 1973. NMR.-study of nitrogen inversion and conformation of 1,5-dihydro-isoalloxazines ('Reduced Flavin'). In: Helvetica Chimica Acta. 1973, 56(2), pp. 630-644. ISSN 0018-019X. eISSN 1522-2675. Available under: doi: 10.1002/hlca.19730560209
BibTex
@article{Tauscher1973NMRst-7448,
  year={1973},
  doi={10.1002/hlca.19730560209},
  title={NMR.-study of nitrogen inversion and conformation of 1,5-dihydro-isoalloxazines ('Reduced Flavin')},
  number={2},
  volume={56},
  issn={0018-019X},
  journal={Helvetica Chimica Acta},
  pages={630--644},
  author={Tauscher, Ludwig and Ghisla, Sandro and Hemmerich, Peter}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/7448">
    <dc:contributor>Tauscher, Ludwig</dc:contributor>
    <dc:creator>Ghisla, Sandro</dc:creator>
    <dc:format>application/pdf</dc:format>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:34:30Z</dcterms:available>
    <dcterms:abstract xml:lang="deu">Thc pyramidal inversion of the N(5)-centre of several reduced flavins was measured by NMR. The inversion barrier was found to be ~10 kcal/mol in acetone solutions and to be independent of the size of the N(5) substituent. An increase of the inversion barrier of ~5 kcal/mol was observed in the case where the N(5) substituent could only be in axial position, and an increase of ~3.5 kcal/mol was observed for an acyl-like N(5) substituent. In aqueous solution the inversion barrier increases by ~3 kcal/mol. The stereochemistry of reduced flavin and its potential relevance in flavin-dependent biological dehydrogenations is discussed.</dcterms:abstract>
    <dc:rights>Attribution-NonCommercial-NoDerivs 2.0 Generic</dc:rights>
    <dc:contributor>Ghisla, Sandro</dc:contributor>
    <dc:contributor>Hemmerich, Peter</dc:contributor>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/7448/1/NMR.pdf"/>
    <dcterms:issued>1973</dcterms:issued>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/7448"/>
    <dcterms:bibliographicCitation>First publ. in: Helvetica Chimica Acta 56 (1973), 2, pp. 630-644</dcterms:bibliographicCitation>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:language>eng</dc:language>
    <dc:creator>Hemmerich, Peter</dc:creator>
    <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by-nc-nd/2.0/"/>
    <dcterms:title>NMR.-study of nitrogen inversion and conformation of 1,5-dihydro-isoalloxazines ('Reduced Flavin')</dcterms:title>
    <dc:creator>Tauscher, Ludwig</dc:creator>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:34:30Z</dc:date>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/7448/1/NMR.pdf"/>
  </rdf:Description>
</rdf:RDF>

Interner Vermerk

xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter

Kontakt
URL der Originalveröffentl.

Prüfdatum der URL

Prüfungsdatum der Dissertation

Finanzierungsart

Kommentar zur Publikation

Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Nein
Begutachtet
Diese Publikation teilen