Synthesis of Epothilones via a Silicon-Tethered RCM Reaction

Gaich, Tanja; Mulzer, Johann

Synthesis of Epothilones via a Silicon-Tethered RCM Reaction

Dateien

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Datum

2005

Autor:innen

Gaich, Tanja

Mulzer, Johann

DOI (zitierfähiger Link)

https://doi.org/10.1021/ol0500923

Sammlungen

Chemie

Publikationstyp

Zeitschriftenartikel

Publikationsstatus

Published

Erschienen in

Organic Letters. 2005, 7(7), pp. 1311-1313. ISSN 1523-7060. eISSN 1523-7052. Available under: doi: 10.1021/ol0500923

Zusammenfassung

A short synthesis of epothilone B and D is reported. The key step for generating the C12-13-trisubstituted Z-double bond uses a ring-closing metathesis reaction of a disiloxane to form a nine-membered silicon-tethered ring.

Fachgebiet (DDC)

540 Chemie

Zitieren

ISO 690

GAICH, Tanja, Johann MULZER, 2005. Synthesis of Epothilones via a Silicon-Tethered RCM Reaction. In: Organic Letters. 2005, 7(7), pp. 1311-1313. ISSN 1523-7060. eISSN 1523-7052. Available under: doi: 10.1021/ol0500923

BibTex

@article{Gaich2005-03-31Synth-40452,
  year={2005},
  doi={10.1021/ol0500923},
  title={Synthesis of Epothilones via a Silicon-Tethered RCM Reaction},
  number={7},
  volume={7},
  issn={1523-7060},
  journal={Organic Letters},
  pages={1311--1313},
  author={Gaich, Tanja and Mulzer, Johann}
}

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