Publikation:

FluxMap : A VANTED add-on for the visual exploration of flux distributions in biological networks

Vorschaubild

Dateien

Rohn_0-396402.pdf
Rohn_0-396402.pdfGröße: 1.34 MBDownloads: 335

Datum

2012

Autor:innen

Rohn, Hendrik
Hartmann, Anja
Junker, Astrid
Junker, Björn H.

Herausgeber:innen

Kontakt

ISSN der Zeitschrift

Electronic ISSN

ISBN

Bibliografische Daten

Verlag

Schriftenreihe

Auflagebezeichnung

URI (zitierfähiger Link)
http://nbn-resolving.de/urn:nbn:de:bsz:352-0-396402
DOI (zitierfähiger Link)
https://doi.org/10.1186/1752-0509-6-33
ArXiv-ID

Internationale Patentnummer

Link zur Lizenz
Attribution 2.0 Generic

Angaben zur Forschungsförderung

Projekt

Open Access-Veröffentlichung
Open Access Gold

Sammlungen

Informatik und Informationswissenschaft: Publikationen
Core Facility der Universität Konstanz

Gesperrt bis

Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

BMC Systems Biology. 2012, 6, 33. eISSN 1752-0509. Available under: doi: 10.1186/1752-0509-6-33

Zusammenfassung

Background

The quantification of metabolic fluxes is gaining increasing importance in the analysis of the metabolic behavior of biological systems such as organisms, tissues or cells. Various methodologies (wetlab or drylab) result in sets of fluxes which require an appropriate visualization for interpretation by scientists. The visualization of flux distributions is a necessary prerequisite for intuitive flux data exploration in the context of metabolic networks.

Results

We present FluxMap, a tool for the advanced visualization and exploration of flux data in the context of metabolic networks. The template-based flux data import assigns flux values and optional quality parameters (e. g. the confidence interval) to biochemical reactions. It supports the discrimination between mass and substance fluxes, such as C- or N-fluxes. After import, flux data mapping and network-based visualization allow the interactive exploration of the dataset. Various visualization options enable the user to adapt layout and network representation according to individual purposes.

Conclusions

The Vanted add-on FluxMap comprises a comprehensive set of functionalities for visualization and advanced visual exploration of flux distributions in biological networks. It is available as a Java open source tool from http://www.vanted.org/fluxmap.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
004 Informatik

Schlagwörter

Konferenz

Rezension
undefined / . - undefined, undefined

Forschungsvorhaben

Organisationseinheiten

Zeitschriftenheft

Verknüpfte Datensätze

Zitieren

ISO 690ROHN, Hendrik, Anja HARTMANN, Astrid JUNKER, Björn H. JUNKER, Falk SCHREIBER, 2012. FluxMap : A VANTED add-on for the visual exploration of flux distributions in biological networks. In: BMC Systems Biology. 2012, 6, 33. eISSN 1752-0509. Available under: doi: 10.1186/1752-0509-6-33
BibTex
@article{Rohn2012FluxM-38504,
  year={2012},
  doi={10.1186/1752-0509-6-33},
  title={FluxMap : A VANTED add-on for the visual exploration of flux distributions in biological networks},
  volume={6},
  journal={BMC Systems Biology},
  author={Rohn, Hendrik and Hartmann, Anja and Junker, Astrid and Junker, Björn H. and Schreiber, Falk},
  note={Article Number: 33}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/38504">
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/38504/3/Rohn_0-396402.pdf"/>
    <dc:creator>Rohn, Hendrik</dc:creator>
    <dc:creator>Junker, Astrid</dc:creator>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-04-18T12:37:11Z</dcterms:available>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/38504"/>
    <dcterms:title>FluxMap : A VANTED add-on for the visual exploration of flux distributions in biological networks</dcterms:title>
    <dc:creator>Schreiber, Falk</dc:creator>
    <dc:contributor>Schreiber, Falk</dc:contributor>
    <dc:rights>Attribution 2.0 Generic</dc:rights>
    <dc:creator>Junker, Björn H.</dc:creator>
    <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by/2.0/"/>
    <dc:contributor>Hartmann, Anja</dc:contributor>
    <dcterms:abstract xml:lang="eng">Background&lt;br /&gt;&lt;br /&gt;The quantification of metabolic fluxes is gaining increasing importance in the analysis of the metabolic behavior of biological systems such as organisms, tissues or cells. Various methodologies (wetlab or drylab) result in sets of fluxes which require an appropriate visualization for interpretation by scientists. The visualization of flux distributions is a necessary prerequisite for intuitive flux data exploration in the context of metabolic networks.&lt;br /&gt;&lt;br /&gt;Results&lt;br /&gt;&lt;br /&gt;We present FluxMap, a tool for the advanced visualization and exploration of flux data in the context of metabolic networks. The template-based flux data import assigns flux values and optional quality parameters (e. g. the confidence interval) to biochemical reactions. It supports the discrimination between mass and substance fluxes, such as C- or N-fluxes. After import, flux data mapping and network-based visualization allow the interactive exploration of the dataset. Various visualization options enable the user to adapt layout and network representation according to individual purposes.&lt;br /&gt;&lt;br /&gt;Conclusions&lt;br /&gt;&lt;br /&gt;The Vanted add-on FluxMap comprises a comprehensive set of functionalities for visualization and advanced visual exploration of flux distributions in biological networks. It is available as a Java open source tool from http://www.vanted.org/fluxmap.</dcterms:abstract>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/36"/>
    <dcterms:issued>2012</dcterms:issued>
    <dc:contributor>Junker, Björn H.</dc:contributor>
    <dc:contributor>Rohn, Hendrik</dc:contributor>
    <dc:creator>Hartmann, Anja</dc:creator>
    <dc:language>eng</dc:language>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/36"/>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/38504/3/Rohn_0-396402.pdf"/>
    <dc:contributor>Junker, Astrid</dc:contributor>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2017-04-18T12:37:11Z</dc:date>
  </rdf:Description>
</rdf:RDF>

Interner Vermerk

xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter

Kontakt
URL der Originalveröffentl.

Prüfdatum der URL

Prüfungsdatum der Dissertation

Finanzierungsart

Kommentar zur Publikation

Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Nein
Begutachtet
Diese Publikation teilen