Brain organoids and organoid intelligence from ethical, legal, and social points of view

Lade...
Vorschaubild
Dateien
Zu diesem Dokument gibt es keine Dateien.
Datum
2024
Autor:innen
Morales Pantoja, Itzy E.
Smirnova, Lena
Herausgeber:innen
Kontakt
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
ArXiv-ID
Internationale Patentnummer
Link zur Lizenz
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Open Access Gold
Sammlungen
Core Facility der Universität Konstanz
Gesperrt bis
Titel in einer weiteren Sprache
Forschungsvorhaben
Organisationseinheiten
Zeitschriftenheft
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published
Erschienen in
Frontiers in Artificial Intelligence. Frontiers. 2024, 6, 1307613. eISSN 2624-8212. Available under: doi: 10.3389/frai.2023.1307613
Zusammenfassung

Human brain organoids, aka cerebral organoids or earlier “mini-brains”, are 3D cellular models that recapitulate aspects of the developing human brain. They show tremendous promise for advancing our understanding of neurodevelopment and neurological disorders. However, the unprecedented ability to model human brain development and function in vitro also raises complex ethical, legal, and social challenges. Organoid Intelligence (OI) describes the ongoing movement to combine such organoids with Artificial Intelligence to establish basic forms of memory and learning. This article discusses key issues regarding the scientific status and prospects of brain organoids and OI, conceptualizations of consciousness and the mind–brain relationship, ethical and legal dimensions, including moral status, human–animal chimeras, informed consent, and governance matters, such as oversight and regulation. A balanced framework is needed to allow vital research while addressing public perceptions and ethical concerns. Interdisciplinary perspectives and proactive engagement among scientists, ethicists, policymakers, and the public can enable responsible translational pathways for organoid technology. A thoughtful, proactive governance framework might be needed to ensure ethically responsible progress in this promising field.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
570 Biowissenschaften, Biologie
Schlagwörter
microphysiological systems, cognition, intelligence, social sciences, learning and memory, consciousness
Konferenz
Rezension
undefined / . - undefined, undefined
Zitieren
ISO 690HARTUNG, Thomas, Itzy E. MORALES PANTOJA, Lena SMIRNOVA, 2024. Brain organoids and organoid intelligence from ethical, legal, and social points of view. In: Frontiers in Artificial Intelligence. Frontiers. 2024, 6, 1307613. eISSN 2624-8212. Available under: doi: 10.3389/frai.2023.1307613
BibTex
@article{Hartung2024Brain-69646,
  year={2024},
  doi={10.3389/frai.2023.1307613},
  title={Brain organoids and organoid intelligence from ethical, legal, and social points of view},
  volume={6},
  journal={Frontiers in Artificial Intelligence},
  author={Hartung, Thomas and Morales Pantoja, Itzy E. and Smirnova, Lena},
  note={Article Number: 1307613}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/69646">
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2024-03-20T08:19:25Z</dcterms:available>
    <dc:contributor>Smirnova, Lena</dc:contributor>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dcterms:issued>2024</dcterms:issued>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/69646/1/Hartung_2-4a7lad7tpljo4.pdf"/>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:creator>Morales Pantoja, Itzy E.</dc:creator>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:contributor>Hartung, Thomas</dc:contributor>
    <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by/4.0/"/>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/69646/1/Hartung_2-4a7lad7tpljo4.pdf"/>
    <dc:creator>Smirnova, Lena</dc:creator>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/69646"/>
    <dc:language>eng</dc:language>
    <dc:creator>Hartung, Thomas</dc:creator>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2024-03-20T08:19:25Z</dc:date>
    <dcterms:title>Brain organoids and organoid intelligence from ethical, legal, and social points of view</dcterms:title>
    <dc:contributor>Morales Pantoja, Itzy E.</dc:contributor>
    <dcterms:abstract>Human brain organoids, aka cerebral organoids or earlier “mini-brains”, are 3D cellular models that recapitulate aspects of the developing human brain. They show tremendous promise for advancing our understanding of neurodevelopment and neurological disorders. However, the unprecedented ability to model human brain development and function in vitro also raises complex ethical, legal, and social challenges. Organoid Intelligence (OI) describes the ongoing movement to combine such organoids with Artificial Intelligence to establish basic forms of memory and learning. This article discusses key issues regarding the scientific status and prospects of brain organoids and OI, conceptualizations of consciousness and the mind–brain relationship, ethical and legal dimensions, including moral status, human–animal chimeras, informed consent, and governance matters, such as oversight and regulation. A balanced framework is needed to allow vital research while addressing public perceptions and ethical concerns. Interdisciplinary perspectives and proactive engagement among scientists, ethicists, policymakers, and the public can enable responsible translational pathways for organoid technology. A thoughtful, proactive governance framework might be needed to ensure ethically responsible progress in this promising field.</dcterms:abstract>
    <dc:rights>Attribution 4.0 International</dc:rights>
  </rdf:Description>
</rdf:RDF>
Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Kontakt
URL der Originalveröffentl.
Prüfdatum der URL
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Ja
Diese Publikation teilen