Publikation: Brain organoids and organoid intelligence from ethical, legal, and social points of view
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Human brain organoids, aka cerebral organoids or earlier “mini-brains”, are 3D cellular models that recapitulate aspects of the developing human brain. They show tremendous promise for advancing our understanding of neurodevelopment and neurological disorders. However, the unprecedented ability to model human brain development and function in vitro also raises complex ethical, legal, and social challenges. Organoid Intelligence (OI) describes the ongoing movement to combine such organoids with Artificial Intelligence to establish basic forms of memory and learning. This article discusses key issues regarding the scientific status and prospects of brain organoids and OI, conceptualizations of consciousness and the mind–brain relationship, ethical and legal dimensions, including moral status, human–animal chimeras, informed consent, and governance matters, such as oversight and regulation. A balanced framework is needed to allow vital research while addressing public perceptions and ethical concerns. Interdisciplinary perspectives and proactive engagement among scientists, ethicists, policymakers, and the public can enable responsible translational pathways for organoid technology. A thoughtful, proactive governance framework might be needed to ensure ethically responsible progress in this promising field.
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HARTUNG, Thomas, Itzy E. MORALES PANTOJA, Lena SMIRNOVA, 2024. Brain organoids and organoid intelligence from ethical, legal, and social points of view. In: Frontiers in Artificial Intelligence. Frontiers. 2024, 6, 1307613. eISSN 2624-8212. Available under: doi: 10.3389/frai.2023.1307613BibTex
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title={Brain organoids and organoid intelligence from ethical, legal, and social points of view},
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journal={Frontiers in Artificial Intelligence},
author={Hartung, Thomas and Morales Pantoja, Itzy E. and Smirnova, Lena},
note={Article Number: 1307613}
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