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Approximate model reductions for combinatorial reaction systems

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2013

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Koeppl, Heinz

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European Control Conference (ECC) : 2013 : 17 - 19 July 2013 : ETH Zurich. Piscataway, NJ: IEEE, 2013. ISBN 978-3-033-03962-9

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The paper considers a model reduction technique that is well-suited for biochemical reaction systems giving rise to the assembly of a large number of different molecular species. The reduction is performed by grouping species with common properties, directly from the model specification in terms of a rule-based language. In recent works, general algorithms for the exact reductions of rule-based models were established, but the state space often remains combinatorial. We extend this line of research by introducing approximate reductions, and an error measure which allows us to quantitatively study the effect of approximate model reductions.

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Control Conference : ECC : 2013, 17. Juli 2013 - 19. Juli 2013, Zürich
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ISO 690PETROV, Tatjana, Heinz KOEPPL, 2013. Approximate model reductions for combinatorial reaction systems. Control Conference : ECC : 2013. Zürich, 17. Juli 2013 - 19. Juli 2013. In: European Control Conference (ECC) : 2013 : 17 - 19 July 2013 : ETH Zurich. Piscataway, NJ: IEEE, 2013. ISBN 978-3-033-03962-9
BibTex
@inproceedings{Petrov2013Appro-42229,
  year={2013},
  title={Approximate model reductions for combinatorial reaction systems},
  url={https://ieeexplore.ieee.org/document/6669734/},
  isbn={978-3-033-03962-9},
  publisher={IEEE},
  address={Piscataway, NJ},
  booktitle={European Control Conference (ECC) :  2013 : 17 - 19 July 2013 : ETH Zurich},
  author={Petrov, Tatjana and Koeppl, Heinz}
}
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2018-04-30

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