Nodal and BMP dispersal during early zebrafish development
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2019
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Rogers, Katherine W.
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Developmental Biology. Elsevier. 2019, 447(1), pp. 14-23. ISSN 0012-1606. eISSN 1095-564X. Available under: doi: 10.1016/j.ydbio.2018.04.002
Zusammenfassung
The secreted TGF-β superfamily signals Nodal and BMP coordinate the patterning of vertebrate embryos. Nodal specifies endoderm and mesoderm during germ layer formation, and BMP specifies ventral fates and patterns the dorsal/ventral axis. Five major models have been proposed to explain how the correct distributions of Nodal and BMP are achieved within tissues to orchestrate embryogenesis: source/sink, transcriptional determination, relay, self-regulation, and shuttling. Here, we discuss recent experiments probing these signal dispersal models, focusing on early zebrafish development.
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570 Biowissenschaften, Biologie
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ROGERS, Katherine W., Patrick MÜLLER, 2019. Nodal and BMP dispersal during early zebrafish development. In: Developmental Biology. Elsevier. 2019, 447(1), pp. 14-23. ISSN 0012-1606. eISSN 1095-564X. Available under: doi: 10.1016/j.ydbio.2018.04.002BibTex
@article{Rogers2019Nodal-55565, year={2019}, doi={10.1016/j.ydbio.2018.04.002}, title={Nodal and BMP dispersal during early zebrafish development}, number={1}, volume={447}, issn={0012-1606}, journal={Developmental Biology}, pages={14--23}, author={Rogers, Katherine W. and Müller, Patrick} }
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