Publikation:

Nodal and BMP dispersal during early zebrafish development

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Rogers_2-2zyglpt8nokk4.pdf
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Datum

2019

Autor:innen

Rogers, Katherine W.

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http://nbn-resolving.de/urn:nbn:de:bsz:352-2-2zyglpt8nokk4
DOI (zitierfähiger Link)
https://doi.org/10.1016/j.ydbio.2018.04.002
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Open Access-Veröffentlichung
Open Access Green

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Biologie: Publikationen
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Published

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Developmental Biology. Elsevier. 2019, 447(1), pp. 14-23. ISSN 0012-1606. eISSN 1095-564X. Available under: doi: 10.1016/j.ydbio.2018.04.002

Zusammenfassung

The secreted TGF-β superfamily signals Nodal and BMP coordinate the patterning of vertebrate embryos. Nodal specifies endoderm and mesoderm during germ layer formation, and BMP specifies ventral fates and patterns the dorsal/ventral axis. Five major models have been proposed to explain how the correct distributions of Nodal and BMP are achieved within tissues to orchestrate embryogenesis: source/sink, transcriptional determination, relay, self-regulation, and shuttling. Here, we discuss recent experiments probing these signal dispersal models, focusing on early zebrafish development.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
570 Biowissenschaften, Biologie

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ISO 690ROGERS, Katherine W., Patrick MÜLLER, 2019. Nodal and BMP dispersal during early zebrafish development. In: Developmental Biology. Elsevier. 2019, 447(1), pp. 14-23. ISSN 0012-1606. eISSN 1095-564X. Available under: doi: 10.1016/j.ydbio.2018.04.002
BibTex
@article{Rogers2019Nodal-55565,
  year={2019},
  doi={10.1016/j.ydbio.2018.04.002},
  title={Nodal and BMP dispersal during early zebrafish development},
  number={1},
  volume={447},
  issn={0012-1606},
  journal={Developmental Biology},
  pages={14--23},
  author={Rogers, Katherine W. and Müller, Patrick}
}
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