Nodal and BMP dispersal during early zebrafish development

Thumbnail Image
Files
Rogers_2-2zyglpt8nokk4.pdf(1.47 MB)
Date
2019
Authors
Rogers, Katherine W.
Editors
Contact
Journal ISSN
Electronic ISSN
ISBN
Bibliographical data
Publisher
Series
URI (citable link)
urn:nbn:de:bsz:352-2-2zyglpt8nokk4
DOI (citable link)
10.1016/j.ydbio.2018.04.002
ArXiv-ID
International patent number
Link to the license
In Copyright
EU project number
Project
Open Access publication
Collections
Biologie
Restricted until
Title in another language
Research Projects
Organizational Units
Journal Issue
Publication type
Journal article
Publication status
Published
Published in
Developmental Biology ; 447 (2019), 1. - pp. 14-23. - Elsevier. - ISSN 0012-1606. - eISSN 1095-564X
Abstract
The secreted TGF-β superfamily signals Nodal and BMP coordinate the patterning of vertebrate embryos. Nodal specifies endoderm and mesoderm during germ layer formation, and BMP specifies ventral fates and patterns the dorsal/ventral axis. Five major models have been proposed to explain how the correct distributions of Nodal and BMP are achieved within tissues to orchestrate embryogenesis: source/sink, transcriptional determination, relay, self-regulation, and shuttling. Here, we discuss recent experiments probing these signal dispersal models, focusing on early zebrafish development.
Summary in another language
Subject (DDC)
570 Biosciences, Biology
Keywords
Conference
Review
undefined / . - undefined, undefined. - (undefined; undefined)
Cite This
ISO 690ROGERS, Katherine W., Patrick MÜLLER, 2019. Nodal and BMP dispersal during early zebrafish development. In: Developmental Biology. Elsevier. 447(1), pp. 14-23. ISSN 0012-1606. eISSN 1095-564X. Available under: doi: 10.1016/j.ydbio.2018.04.002
BibTex
@article{Rogers2019Nodal-55565,
  year={2019},
  doi={10.1016/j.ydbio.2018.04.002},
  title={Nodal and BMP dispersal during early zebrafish development},
  number={1},
  volume={447},
  issn={0012-1606},
  journal={Developmental Biology},
  pages={14--23},
  author={Rogers, Katherine W. and Müller, Patrick}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/55565">
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dcterms:issued>2019</dcterms:issued>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/55565/1/Rogers_2-2zyglpt8nokk4.pdf"/>
    <dc:rights>terms-of-use</dc:rights>
    <dcterms:title>Nodal and BMP dispersal during early zebrafish development</dcterms:title>
    <dc:language>eng</dc:language>
    <dc:contributor>Rogers, Katherine W.</dc:contributor>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2021-11-16T13:26:20Z</dc:date>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/55565"/>
    <dcterms:abstract xml:lang="eng">The secreted TGF-β superfamily signals Nodal and BMP coordinate the patterning of vertebrate embryos. Nodal specifies endoderm and mesoderm during germ layer formation, and BMP specifies ventral fates and patterns the dorsal/ventral axis. Five major models have been proposed to explain how the correct distributions of Nodal and BMP are achieved within tissues to orchestrate embryogenesis: source/sink, transcriptional determination, relay, self-regulation, and shuttling. Here, we discuss recent experiments probing these signal dispersal models, focusing on early zebrafish development.</dcterms:abstract>
    <dc:contributor>Müller, Patrick</dc:contributor>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2021-11-16T13:26:20Z</dcterms:available>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:creator>Müller, Patrick</dc:creator>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/55565/1/Rogers_2-2zyglpt8nokk4.pdf"/>
    <dc:creator>Rogers, Katherine W.</dc:creator>
  </rdf:Description>
</rdf:RDF>
Internal note
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Contact
URL of original publication
Test date of URL
Examination date of dissertation
Method of financing
Comment on publication
Alliance license
Corresponding Authors der Uni Konstanz vorhanden
International Co-Authors
Bibliography of Konstanz
No
Refereed
Yes