Dose shift effects on an apomorphine-elicited response
Dose shift effects on an apomorphine-elicited response
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2000
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Medical Science Research ; 28 (2000). - pp. 39-42. - ISSN 0269-8951
Abstract
Apomorphine (Apo) a dopaminergic agonist, elicited protracted bouts of pecking when injected intramuscularly into pigeons. Repeated injections of either a small or a large dose of Apo into two separate groups of pigeons led to progressive increments in pecking up to two different asymptotic response levels (dose-related sensitization). A subsequent switch of the Apo doses between the groups yielded two statistically undistinguishable asymptotic response levels. A smaller dose of Apo induced a significantly higher asymptotic response if the pigeons pre-treated with a larger dose than if they had not. The results are discussed in relation to a simple classical conditioning model of sensitization, and are related to behavioural contrast phenomena that occur in conventional conditioning paradigms involving changes of food reward magnitudes.
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150 Psychology
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DELIUS, Juan, Adriana GODOY, Martina SIEMANN, 2000. Dose shift effects on an apomorphine-elicited response. In: Medical Science Research. 28, pp. 39-42. ISSN 0269-8951BibTex
@article{Delius2000shift-20681, year={2000}, title={Dose shift effects on an apomorphine-elicited response}, volume={28}, issn={0269-8951}, journal={Medical Science Research}, pages={39--42}, author={Delius, Juan and Godoy, Adriana and Siemann, Martina} }
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