Corticosterone suppresses cutaneous immune function in temperate but not tropical House Sparrows, Passer domesticus

Lade...
Vorschaubild
Dateien
Zu diesem Dokument gibt es keine Dateien.
Datum
2005
Autor:innen
Martin, Lynn B.
Gilliam, Jessica
Han, Peggy
Lee, Kelly
Herausgeber:innen
Kontakt
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
URI (zitierfähiger Link)
ArXiv-ID
Internationale Patentnummer
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Sammlungen
Core Facility der Universität Konstanz
Gesperrt bis
Titel in einer weiteren Sprache
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published
Erschienen in
General and Comparative Endocrinology. 2005, 140(2), pp. 126-135. ISSN 0016-6480. eISSN 1095-6840. Available under: doi: 10.1016/j.ygcen.2004.10.010
Zusammenfassung

Levels of corticosterone (CORT), the primary avian stress hormone, tend to vary over space and time in passerines, but why this is so remains unclear. One reason may be differential need for immune defense. Typically, sustained high levels of CORT suppress immune activity in vertebrates. Thus, animals living where parasite threats are high might maintain low levels of CORT and mount weak CORT stress responses to ensure that their immune defenses are in a high state of readiness at all times. Here, we addressed this hypothesis by comparing CORT levels in two populations of House Sparrows (Passer domesticus), one from the tropics (Colon, Panama) where parasite threats are high and one from the North-temperate zone (New Jersey, USA) where they are lower. Indeed, we found that House Sparrows from Panama had lower baseline and stress-induced CORT levels than House Sparrows from New Jersey. To more directly test our hypothesis, we artificially elevated CORT (via implant) in both populations of birds, expecting that cutaneous immune activity (induced by phytohemagglutinin (PHA)) would be suppressed as it is in most vertebrates studied to date. Surprisingly, we found that CORT implants did not affect immune function in Panamanian sparrows, while immune function in (non-breeding) New Jersey sparrows was suppressed. This suggests that Panamanian House Sparrows may be immunologically insensitive to CORT, in addition to maintaining low baseline and stress-induced levels of this hormone. We propose that other animals living where disease threats are high may use CORT in a similar way.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
570 Biowissenschaften, Biologie
Schlagwörter
Defense; Latitude; Life history; Phytohemagglutinin; Steroids; Stress
Konferenz
Rezension
undefined / . - undefined, undefined
Forschungsvorhaben
Organisationseinheiten
Zeitschriftenheft
Datensätze
Zitieren
ISO 690MARTIN, Lynn B., Jessica GILLIAM, Peggy HAN, Kelly LEE, Martin WIKELSKI, 2005. Corticosterone suppresses cutaneous immune function in temperate but not tropical House Sparrows, Passer domesticus. In: General and Comparative Endocrinology. 2005, 140(2), pp. 126-135. ISSN 0016-6480. eISSN 1095-6840. Available under: doi: 10.1016/j.ygcen.2004.10.010
BibTex
@article{Martin2005-01-15Corti-42396,
  year={2005},
  doi={10.1016/j.ygcen.2004.10.010},
  title={Corticosterone suppresses cutaneous immune function in temperate but not tropical House Sparrows, Passer domesticus},
  number={2},
  volume={140},
  issn={0016-6480},
  journal={General and Comparative Endocrinology},
  pages={126--135},
  author={Martin, Lynn B. and Gilliam, Jessica and Han, Peggy and Lee, Kelly and Wikelski, Martin}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/42396">
    <dc:contributor>Gilliam, Jessica</dc:contributor>
    <dcterms:abstract xml:lang="eng">Levels of corticosterone (CORT), the primary avian stress hormone, tend to vary over space and time in passerines, but why this is so remains unclear. One reason may be differential need for immune defense. Typically, sustained high levels of CORT suppress immune activity in vertebrates. Thus, animals living where parasite threats are high might maintain low levels of CORT and mount weak CORT stress responses to ensure that their immune defenses are in a high state of readiness at all times. Here, we addressed this hypothesis by comparing CORT levels in two populations of House Sparrows (Passer domesticus), one from the tropics (Colon, Panama) where parasite threats are high and one from the North-temperate zone (New Jersey, USA) where they are lower. Indeed, we found that House Sparrows from Panama had lower baseline and stress-induced CORT levels than House Sparrows from New Jersey. To more directly test our hypothesis, we artificially elevated CORT (via implant) in both populations of birds, expecting that cutaneous immune activity (induced by phytohemagglutinin (PHA)) would be suppressed as it is in most vertebrates studied to date. Surprisingly, we found that CORT implants did not affect immune function in Panamanian sparrows, while immune function in (non-breeding) New Jersey sparrows was suppressed. This suggests that Panamanian House Sparrows may be immunologically insensitive to CORT, in addition to maintaining low baseline and stress-induced levels of this hormone. We propose that other animals living where disease threats are high may use CORT in a similar way.</dcterms:abstract>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dc:creator>Wikelski, Martin</dc:creator>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2018-05-17T12:55:38Z</dcterms:available>
    <dc:contributor>Martin, Lynn B.</dc:contributor>
    <dc:creator>Han, Peggy</dc:creator>
    <dc:contributor>Wikelski, Martin</dc:contributor>
    <dc:language>eng</dc:language>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:contributor>Han, Peggy</dc:contributor>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/42396"/>
    <dcterms:issued>2005-01-15</dcterms:issued>
    <dc:creator>Martin, Lynn B.</dc:creator>
    <dc:contributor>Lee, Kelly</dc:contributor>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:creator>Lee, Kelly</dc:creator>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2018-05-17T12:55:38Z</dc:date>
    <dc:creator>Gilliam, Jessica</dc:creator>
    <dcterms:title>Corticosterone suppresses cutaneous immune function in temperate but not tropical House Sparrows, Passer domesticus</dcterms:title>
  </rdf:Description>
</rdf:RDF>
Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Kontakt
URL der Originalveröffentl.
Prüfdatum der URL
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Nein
Begutachtet
Diese Publikation teilen