Hierarchical DL-Glutamic acid microspheres from polymer-induced liquid precursors

Lade...
Vorschaubild
Dateien
Yuan Hierarchical Microspheres--.pdf
Yuan Hierarchical Microspheres--.pdfGröße: 1.9 MBDownloads: 384
Datum
2011
Autor:innen
Jiang, Yuan
Gower, Laurie
Volkmer, Dirk
Herausgeber:innen
Kontakt
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
DOI (zitierfähiger Link)
ArXiv-ID
Internationale Patentnummer
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Open Access Green
Sammlungen
Core Facility der Universität Konstanz
Gesperrt bis
Titel in einer weiteren Sprache
Forschungsvorhaben
Organisationseinheiten
Zeitschriftenheft
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published
Erschienen in
Zusammenfassung

Nanostructured organic crystals have a broad application potential as pharmaceuticals, pigments, or catalysts. The development of facile and reproducible synthetic routes and the upscaling of the process, however, still remain a challenge. Here, we describe the synthesis of macroporous hierarchically structured microspheres with nanoplatelets as building blocks of a model organic molecule—DL-glutamic acid (DL-Glu)—via a polymer-induced liquid precursor (PILP) phase using oppositely charged polyethylene imine (PEI) as a polymeric additive. The impacts of experimental parameters such as [DL-Glu], temperature, solvent composition, and the pH value were systematically investigated for the DL-Glu morphosynthesis process. A mechanism is suggested to explain the precipitation of DL-Glu with PEI as an additive based on a multistep process: (1) the formation, growth, and coalescence of the PILP droplets; (2) the homogeneous nucleation of nanoplatelets within PILP droplets and (3) the reorientation of nanoplatelets into hierarchical microspheres. This model system can be further extended to the precipitation of other amino acids that have a net charge opposite to that of the polyelectrolyte additive.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
540 Chemie
Schlagwörter
Konferenz
Rezension
undefined / . - undefined, undefined
Zitieren
ISO 690JIANG, Yuan, Laurie GOWER, Dirk VOLKMER, Helmut CÖLFEN, 2011. Hierarchical DL-Glutamic acid microspheres from polymer-induced liquid precursors. In: Crystal Growth & Design. 2011, 11(7), pp. 3243-3249. ISSN 1528-7483. Available under: doi: 10.1021/cg200504n
BibTex
@article{Jiang2011Hiera-18748,
  year={2011},
  doi={10.1021/cg200504n},
  title={Hierarchical DL-Glutamic acid microspheres from polymer-induced liquid precursors},
  number={7},
  volume={11},
  issn={1528-7483},
  journal={Crystal Growth & Design},
  pages={3243--3249},
  author={Jiang, Yuan and Gower, Laurie and Volkmer, Dirk and Cölfen, Helmut}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/18748">
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dc:contributor>Cölfen, Helmut</dc:contributor>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2012-03-28T09:54:15Z</dcterms:available>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/18748/2/Yuan%20Hierarchical%20Microspheres--.pdf"/>
    <dcterms:title>Hierarchical DL-Glutamic acid microspheres from polymer-induced liquid precursors</dcterms:title>
    <dcterms:abstract xml:lang="eng">Nanostructured organic crystals have a broad application potential as pharmaceuticals, pigments, or catalysts. The development of facile and reproducible synthetic routes and the upscaling of the process, however, still remain a challenge. Here, we describe the synthesis of macroporous hierarchically structured microspheres with nanoplatelets as building blocks of a model organic molecule—DL-glutamic acid (DL-Glu)—via a polymer-induced liquid precursor (PILP) phase using oppositely charged polyethylene imine (PEI) as a polymeric additive. The impacts of experimental parameters such as [DL-Glu], temperature, solvent composition, and the pH value were systematically investigated for the DL-Glu morphosynthesis process. A mechanism is suggested to explain the precipitation of DL-Glu with PEI as an additive based on a multistep process: (1) the formation, growth, and coalescence of the PILP droplets; (2) the homogeneous nucleation of nanoplatelets within PILP droplets and (3) the reorientation of nanoplatelets into hierarchical microspheres. This model system can be further extended to the precipitation of other amino acids that have a net charge opposite to that of the polyelectrolyte additive.</dcterms:abstract>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/18748"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2012-03-28T09:54:15Z</dc:date>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <dc:creator>Gower, Laurie</dc:creator>
    <dc:creator>Jiang, Yuan</dc:creator>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <dc:language>eng</dc:language>
    <dc:creator>Volkmer, Dirk</dc:creator>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <dc:rights>terms-of-use</dc:rights>
    <dc:contributor>Jiang, Yuan</dc:contributor>
    <dc:creator>Cölfen, Helmut</dc:creator>
    <dcterms:issued>2011</dcterms:issued>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dcterms:bibliographicCitation>First publ. in: Crystal growth &amp; design ; 11 (2011), 7. - S. 3243–3249</dcterms:bibliographicCitation>
    <dc:contributor>Volkmer, Dirk</dc:contributor>
    <dc:contributor>Gower, Laurie</dc:contributor>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/18748/2/Yuan%20Hierarchical%20Microspheres--.pdf"/>
  </rdf:Description>
</rdf:RDF>
Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Kontakt
URL der Originalveröffentl.
Prüfdatum der URL
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Diese Publikation teilen