Extracellular IgC2 constant domains of CEACAMs mediate PI3K sensitivity during uptake of pathogens

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2012
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Naujoks, Jan
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urn:nbn:de:bsz:352-218273
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10.1371/journal.pone.0039908
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PLoS ONE ; 7 (2012), 6. - e39908. - eISSN 1932-6203
Abstract
Several pathogenic bacteria utilize receptors of the CEACAM family to attach to human cells. Binding to different members of this receptor family can result in uptake of the bacteria. Uptake of Neisseria gonorrhoeae, a gram-negative human pathogen, via CEACAMs found on epithelial cells, such as CEACAM1, CEA or CEACAM6, differs mechanistically from phagocytosis mediated by CEACAM3, a CEACAM family member expressed selectively by human granulocytes.
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ISO 690VOGES, Maike, Verena BACHMANN, Jan NAUJOKS, Kathrin KOPP, Christof R. HAUCK, 2012. Extracellular IgC2 constant domains of CEACAMs mediate PI3K sensitivity during uptake of pathogens. In: PLoS ONE. 7(6), e39908. eISSN 1932-6203. Available under: doi: 10.1371/journal.pone.0039908
BibTex
@article{Voges2012Extra-21827,
  year={2012},
  doi={10.1371/journal.pone.0039908},
  title={Extracellular Ig<sub>C2</sub> constant domains of CEACAMs mediate PI3K sensitivity during uptake of pathogens},
  number={6},
  volume={7},
  journal={PLoS ONE},
  author={Voges, Maike and Bachmann, Verena and Naujoks, Jan and Kopp, Kathrin and Hauck, Christof R.},
  note={Article Number: e39908}
}
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