Organotypic Models to Study Human Glioblastoma : Studying the Beast in Its Ecosystem
| Type of Publication: | Journal article |
| Publication status: | Published |
| URI (citable link): | http://nbn-resolving.de/urn:nbn:de:bsz:352-2-1mu9mi4rmfyzk2 |
| Author: | Pamies, David; Zurich, Marie-Gabrielle; Hartung, Thomas |
| Year of publication: | 2020 |
| Published in: | iScience ; 23 (2020), 10. - 101633. - Elsevier. - ISSN 2589-0042. - eISSN 2589-0042 |
| Pubmed ID: | 33103073 |
| DOI (citable link): | https://dx.doi.org/10.1016/j.isci.2020.101633 |
| Summary: |
Glioblastoma is a very aggressive primary brain tumor in adults, with very low survival rates and no curative treatments. The high failure rate of drug development for this cancer is linked to the high-cost, time-consuming, and inefficient models used to study the disease. Advances in stem cell and in vitro cultures technologies are promising, however, and here we present the advantages and limitations of available organotypic culture models and discuss their possible applications for studying glioblastoma.
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| Subject (DDC): | 570 Biosciences, Biology |
| Link to License: | Attribution-NonCommercial-NoDerivatives 4.0 International |
| Bibliography of Konstanz: | Yes |
| Refereed: | Yes |
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PAMIES, David, Marie-Gabrielle ZURICH, Thomas HARTUNG, 2020. Organotypic Models to Study Human Glioblastoma : Studying the Beast in Its Ecosystem. In: iScience. Elsevier. 23(10), 101633. ISSN 2589-0042. eISSN 2589-0042. Available under: doi: 10.1016/j.isci.2020.101633
@article{Pamies2020-10-23Organ-52307, title={Organotypic Models to Study Human Glioblastoma : Studying the Beast in Its Ecosystem}, year={2020}, doi={10.1016/j.isci.2020.101633}, number={10}, volume={23}, issn={2589-0042}, journal={iScience}, author={Pamies, David and Zurich, Marie-Gabrielle and Hartung, Thomas}, note={Article Number: 101633} }
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