Correlating in vitro data to in vivo findings for risk assessment

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BALE, Ambuja S., Elaina KENYON, Thomas J. FLYNN, John C. LIPSCOMB, Donna L. NEDRICK, Thomas HARTUNG, Geoffrey W. PATTON, 2014. Correlating in vitro data to in vivo findings for risk assessment. In: Alternatives to Animal Experimentation : ALTEX. 31(1), pp. 79-90. ISSN 0946-7785. eISSN 1868-8551. Available under: doi: 10.14573/altex.1310011

@article{Bale2014Corre-30683, title={Correlating in vitro data to in vivo findings for risk assessment}, year={2014}, doi={10.14573/altex.1310011}, number={1}, volume={31}, issn={0946-7785}, journal={Alternatives to Animal Experimentation : ALTEX}, pages={79--90}, author={Bale, Ambuja S. and Kenyon, Elaina and Flynn, Thomas J. and Lipscomb, John C. and Nedrick, Donna L. and Hartung, Thomas and Patton, Geoffrey W.} }

<rdf:RDF xmlns:dcterms="" xmlns:dc="" xmlns:rdf="" xmlns:bibo="" xmlns:dspace="" xmlns:foaf="" xmlns:void="" xmlns:xsd="" > <rdf:Description rdf:about=""> <dc:creator>Nedrick, Donna L.</dc:creator> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dc:creator>Bale, Ambuja S.</dc:creator> <dc:contributor>Lipscomb, John C.</dc:contributor> <dc:contributor>Patton, Geoffrey W.</dc:contributor> <dc:language>eng</dc:language> <dc:creator>Flynn, Thomas J.</dc:creator> <dcterms:isPartOf rdf:resource=""/> <dc:rights>terms-of-use</dc:rights> <dc:creator>Hartung, Thomas</dc:creator> <dcterms:hasPart rdf:resource=""/> <dc:creator>Kenyon, Elaina</dc:creator> <dc:contributor>Kenyon, Elaina</dc:contributor> <bibo:uri rdf:resource=""/> <dcterms:available rdf:datatype="">2015-04-08T09:16:12Z</dcterms:available> <dspace:hasBitstream rdf:resource=""/> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dc:contributor>Bale, Ambuja S.</dc:contributor> <dcterms:title>Correlating in vitro data to in vivo findings for risk assessment</dcterms:title> <dcterms:rights rdf:resource=""/> <dc:contributor>Nedrick, Donna L.</dc:contributor> <dc:creator>Lipscomb, John C.</dc:creator> <dc:date rdf:datatype="">2015-04-08T09:16:12Z</dc:date> <dspace:isPartOfCollection rdf:resource=""/> <dcterms:abstract xml:lang="eng">A special session at the Toxicology and Risk Assessment Conference in Cincinnati, OH, USA in May, 2012 presented approaches to expand current uses of in vitro toxicity data for risk assessment. Evaluation of xenobiotics through use of in vitro study methods is increasing exponentially and these methodologies offer a relatively fast and considerably cheaper way to determine toxicities in comparison to traditional animal-based approaches. One of the challenges with in vitro data is to effectively use this information for risk assessment purposes. Currently, in vitro studies are used as supportive information for hazard characterization and to identify mechanisms associated with toxicity. Being able to effectively correlate in vitro effects with in vivo observations represents a major challenge for risk assessors. The presentations in this special session provided innovative approaches toward effectively using in vitro data for the human health risk assessment process.</dcterms:abstract> <dc:contributor>Flynn, Thomas J.</dc:contributor> <dc:creator>Patton, Geoffrey W.</dc:creator> <dcterms:issued>2014</dcterms:issued> <dc:contributor>Hartung, Thomas</dc:contributor> </rdf:Description> </rdf:RDF>

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