KOPS - Das Institutionelle Repositorium der Universität Konstanz

Low vagal tone is associated with impaired post stress recovery of cardiovascular, endocrine, and immune markers

Low vagal tone is associated with impaired post stress recovery of cardiovascular, endocrine, and immune markers

Zitieren

Dateien zu dieser Ressource

Prüfsumme: MD5:4c7019ccf75c5247a081b28d2168d981

WEBER, Cora Stefanie, Julian F. THAYER, Miriam RUDAT, Petra H. WIRTZ, Frank ZIMMERMANN-VIEHOFF, Alexander THOMAS, Frank H. PERSCHEL, Petra C. ARCK, Hans C. DETER, 2010. Low vagal tone is associated with impaired post stress recovery of cardiovascular, endocrine, and immune markers. In: European Journal of Applied Physiology. 109(2), pp. 201-211. ISSN 1439-6319. eISSN 1439-6327. Available under: doi: 10.1007/s00421-009-1341-x

@article{Weber2010vagal-30643, title={Low vagal tone is associated with impaired post stress recovery of cardiovascular, endocrine, and immune markers}, year={2010}, doi={10.1007/s00421-009-1341-x}, number={2}, volume={109}, issn={1439-6319}, journal={European Journal of Applied Physiology}, pages={201--211}, author={Weber, Cora Stefanie and Thayer, Julian F. and Rudat, Miriam and Wirtz, Petra H. and Zimmermann-Viehoff, Frank and Thomas, Alexander and Perschel, Frank H. and Arck, Petra C. and Deter, Hans C.} }

<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/rdf/resource/123456789/30643"> <dc:contributor>Wirtz, Petra H.</dc:contributor> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/43"/> <dcterms:issued>2010</dcterms:issued> <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/30643/1/Weber_0-276705.pdf"/> <dc:creator>Deter, Hans C.</dc:creator> <dc:contributor>Arck, Petra C.</dc:contributor> <dc:contributor>Rudat, Miriam</dc:contributor> <foaf:homepage rdf:resource="http://localhost:8080/jspui"/> <dc:creator>Thayer, Julian F.</dc:creator> <dc:contributor>Thomas, Alexander</dc:contributor> <dc:contributor>Zimmermann-Viehoff, Frank</dc:contributor> <dc:creator>Zimmermann-Viehoff, Frank</dc:creator> <dc:creator>Arck, Petra C.</dc:creator> <dc:contributor>Deter, Hans C.</dc:contributor> <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/30643"/> <dcterms:abstract xml:lang="eng">Reduced heart rate variability (HRV) and delayed blood pressure recovery are associated with increased cardiovascular risk. Besides this evident link, the vagus is thought to play an inhibitory role in the regulation of other allostatic systems, including inflammation and the hypothalamic-pituitary-adrenal (HPA) axis. However, human evidence is scarce. To further explore these associations and with special regard to the postulated mediating role of the vagus, we hypothesised that subjects with low vagal tone as indexed by reduced resting HRV would show impaired post-stress recovery of cardiovascular, endocrine and immune system markers involved in cardiovascular pathology. 44 healthy men underwent a standardised mental stress test. Besides continuous measurement of systolic and diastolic blood pressure (SBP, DBP), heart rate (HR), and HRV serum cortisol, tumour necrosis factor-alpha (TNF-alpha), and interleukin-6 (IL-6) were measured before, after, 20, and 60 min after stress. Low versus high HRV groups was defined by median split on resting HRV (RMSSD). The task elicited significant time effects for SBP, DBP, HR, HRV, cortisol, and TNF-alpha. Subjects with low baseline HRV showed almost no modulation of HRV coupled with overall reduced HRV levels, and impaired recovery of DBP, cortisol, and TNF-alpha. Confirming our hypothesis, low vagal tone was associated with impaired recovery of cardiovascular, endocrine, and immune markers in healthy males. The data support an inhibitory role of the vagus in the regulation of allostatic systems as described in the neurovisceral integration model. We posit reduced resting HRV as a risk marker for future cardiovascular and other stress-related disease.</dcterms:abstract> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/rdf/resource/123456789/43"/> <dc:contributor>Weber, Cora Stefanie</dc:contributor> <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/30643/1/Weber_0-276705.pdf"/> <dcterms:rights rdf:resource="http://nbn-resolving.de/urn:nbn:de:bsz:352-20150305140228786-3747162-5"/> <dcterms:title>Low vagal tone is associated with impaired post stress recovery of cardiovascular, endocrine, and immune markers</dcterms:title> <dc:contributor>Thayer, Julian F.</dc:contributor> <dc:creator>Rudat, Miriam</dc:creator> <dc:contributor>Perschel, Frank H.</dc:contributor> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2015-04-01T09:59:31Z</dcterms:available> <dc:creator>Wirtz, Petra H.</dc:creator> <dc:creator>Thomas, Alexander</dc:creator> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2015-04-01T09:59:31Z</dc:date> <dc:language>eng</dc:language> <dc:creator>Weber, Cora Stefanie</dc:creator> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dc:creator>Perschel, Frank H.</dc:creator> </rdf:Description> </rdf:RDF>

Dateiabrufe seit 01.04.2015 (Informationen über die Zugriffsstatistik)

Weber_0-276705.pdf 692

Das Dokument erscheint in:

KOPS Suche


Stöbern

Mein Benutzerkonto