How reggies regulate regeneration and axon growth
| Type of Publication: | Journal article |
| URI (citable link): | http://nbn-resolving.de/urn:nbn:de:bsz:352-191760 |
| Author: | Stürmer, Claudia |
| Year of publication: | 2012 |
| Published in: | Cell and Tissue Research ; 349 (2012), 1. - pp. 71-77. - ISSN 0302-766X. - eISSN 1432-0878 |
| Pubmed ID: | 22350847 |
| DOI (citable link): | https://dx.doi.org/10.1007/s00441-012-1343-6 |
| Summary: |
The microdomain-forming proteins reggie-1 and reggie-2 (alias flotillins) were found to be upregulated in axon-regenerating fish retinal ganglion cells (RGCs). They were subsequently shown to be indispensible for axon regeneration and neurite extension in fish and mammals. Our current concept proposes that reggies-often together with the cellular Prion protein (PrP)-regulate the turnover of membrane and specific membrane proteins at the growth cone, which is the prerequisite for neurite elongation and guidance.
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| Subject (DDC): | 570 Biosciences, Biology |
| Link to License: | In Copyright |
| Bibliography of Konstanz: | Yes |
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STÜRMER, Claudia, 2012. How reggies regulate regeneration and axon growth. In: Cell and Tissue Research. 349(1), pp. 71-77. ISSN 0302-766X. eISSN 1432-0878. Available under: doi: 10.1007/s00441-012-1343-6
@article{Sturmer2012-07reggi-19176, title={How reggies regulate regeneration and axon growth}, year={2012}, doi={10.1007/s00441-012-1343-6}, number={1}, volume={349}, issn={0302-766X}, journal={Cell and Tissue Research}, pages={71--77}, author={Stürmer, Claudia} }
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